VRTX

Vertex Pharmaceuticals
D

VRTX

Arincen81/100B

Vertex Pharmaceuticals financials

Yes. Vertex Pharmaceuticals earned 3.98B USD of net income over the last twelve months, 30.6% of its revenue. It made a profit in 10 of its 36 fiscal years since 1990. Its last loss was in fiscal year 2024.

Revenue (TTM)
12.99B USD
Net income (TTM)
3.98B USD
Free cash flow (TTM)
3.20B USD
Cash and short-term investments
6.30B USD
Total debt
6.48B USD
Shareholders' equity
20.91B USD

Cash, debt and equity as of 30 Sept 2026.

Vertex Pharmaceuticals earnings

Next earnings · Q4 FY2026
EPS estimate
4.23 USD
Revenue estimate
3.50B USD
Last quarter · Q3 FY2026
EPS4.76Missed -1.2%Revenue3.44BBeat +0.6%

Revenue

ReportedEstimate

EPS

ReportedEstimate
PeriodReport dateEPS estimateReported EPSSurpriseEPS growthRevenue estimateReported revenueSurpriseRevenue growth
Q1 FY20274.64——+3.83%3.47B——+16.17%
Q4 FY20264.23——-15.90%3.50B——+9.76%
Q3 FY20264.824.76-1.24%-0.83%3.42B3.44B+0.62%+11.85%
Q2 FY20264.744.73-0.21%+4.65%3.23B3.33B+3.20%+12.45%
Q1 FY20264.244.47+5.42%+10.10%2.99B2.99B-0.24%+7.82%
Q4 FY20255.115.03-1.57%+26.38%3.18B3.19B+0.18%+9.55%
Q3 FY20254.574.80+5.03%+9.59%3.06B3.08B+0.55%+10.99%
Q2 FY20254.294.52+5.36%—2.91B2.96B+2.01%+12.53%

Vertex Pharmaceuticals growth and profitability

Full income statement
Revenue (TTM)
12.99B USD
Net income (TTM)
3.98B USD
Gross margin
85.57%
Operating margin
33.87%
Net margin
30.61%

Revenue / Net income

Revenue Net income Net margin
PeriodRevenueGrowthNet incomeGrowthGross marginOperating marginNet marginEBITDAGrowth
FY202512.07B+9.57%3.95B—85.03%39.43%32.74%4.87B+900.68%
FY202411.02B+11.66%-535.60M-114.80%86.11%-2.11%-4.86%486.30M-89.44%
FY20239.87B+10.51%3.62B+8.96%87.21%38.83%36.68%4.61B+3.83%
FY20228.93B+17.91%3.32B+41.84%87.90%48.23%37.20%4.44B+52.03%
FY20217.57B+22.06%2.34B-13.63%88.06%36.73%30.92%2.92B-11.17%

How Vertex Pharmaceuticals makes its money

TRIKAFTA/KAFTRIO10.31B 85.4%
ALYFTREK837.80M 6.9%
Manufactured Product, Other820.10M 6.8%
Revenue12.07B 100.0%
Cost of revenue1.81B 15.0%
Gross profit10.27B 85.0%
Research and development3.75B 31.1%
Selling and administration1.75B 14.5%
Operating income4.76B 39.4%
Tax690.00M 5.7%
Other expense117.50M 1.0%
Net income3.95B 32.7%

FY2025, in USD. Each band is as wide as its money; the percentage is its share of revenue.

Vertex Pharmaceuticals revenue breakdown

By product

FY2025
TRIKAFTA/KAFTRIO: 86.2%ALYFTREK: 7.0%Manufactured Product, Other: 6.9%86.2%TRIKAFTA/KAFTRIO7.0%ALYFTREK6.9%Manufactured Product, Other
SegmentRevenueShare of revenueChange on the year
TRIKAFTA/KAFTRIO10.31B86.2%+0.7%
ALYFTREK837.80M7.0%—
Manufactured Product, Other820.10M6.9%+4.9%

By region

FY2025
United States: 45.9%Non-US: 33.1%Europe: 21.0%45.9%United States33.1%Non-US21.0%Europe
RegionRevenueShare of revenueChange on the year
United States7.55B45.9%+12.9%
Non-US5.45B33.1%—
Europe3.46B21.0%+0.2%

Operating and free cash flow

Full cash flow statement
Operating cash flow Free cash flow
Fiscal yearOperating cash flowFree cash flow
FY20253.63B3.19B
FY2024-492.60M-790.30M
FY20233.54B3.28B
FY20224.13B3.93B
FY20212.64B2.41B
FY20203.25B2.99B
FY20191.57B1.49B
FY20181.27B1.17B
FY2017844.94M585.52M
FY2016236.10M179.54M

Vertex Pharmaceuticals financial health

Full balance sheet
Cash and short-term investments
6.30B USD
Total debt
6.48B USD
Net cash
-175.10M USD
Free cash flow (TTM)
3.20B USD
Current ratio
2.34
Debt to equity
0.31
Piotroski score
4 / 9
Altman Z-score
8.86

Cash, debt and free cash flow

Cash and short-term investments Total debt Free cash flow
Fiscal yearCash and short-term investmentsTotal debtFree cash flow
FY20256.61B3.88B3.19B
FY20246.12B1.75B-790.30M
FY202311.22B808.40M3.28B
FY202210.78B899.70M3.93B
FY20217.52B967.40M2.41B

Assets, liabilities and equity

Total assets Total liabilities Shareholders' equity
Fiscal yearTotal assetsTotal liabilitiesShareholders' equity
FY202526.14B7.48B18.67B
FY202422.53B6.12B16.41B
FY202322.73B5.15B17.58B
FY202218.15B4.24B13.91B
FY202113.43B3.33B10.10B
FY202011.75B3.07B8.69B
FY20198.32B2.23B6.09B
FY20186.25B1.81B4.44B
FY20173.55B1.50B2.03B
FY20162.89B1.56B1.16B

Vertex Pharmaceuticals valuation

Price to earnings ratio (TTM)
34.93
Forward P/E (FY2026)
30.00
Price to sales (TTM)
10.67
Price to book
6.63
EV / EBITDA (TTM)
27.95

Capital structure

Market capitalization
138.65B USD
+
Total debt
6.48B USD
−
Cash and short-term investments
6.30B USD
=
Enterprise value
138.83B USD

Valuation over time

P/EForward P/EForward P/E · EstimateEstimate
Fiscal yearP/EForward P/EP/SP/BEV/EBITDA
FY2028 (est.)22.71————
FY2027 (est.)27.1322.71———
FY2026 (est.)30.0027.13———
Now (TTM)34.9327.5110.676.6327.95
FY202529.3224.889.606.2123.57
FY2024-193.6121.799.416.32207.43
FY202328.9615.0410.625.9620.69
FY202222.2715.048.285.3214.51
FY202124.1615.047.475.6017.40

Vertex Pharmaceuticals against its own history

Each figure in the latest fiscal year against the same figure from FY2021 to FY2025: the range, its median (the line) and the latest (the dot, green on the good side of the median). The P/E is today's against its daily readings of five years.

Its peers: Moderna, Regeneron Pharmaceuticals, Revolution Medicines, United Therapeutics, Incyte, and Insmed, the US Biotechnology companies closest to it in size, each in its own latest fiscal year: their median (the line) and its rank among them, first being the best.

  • Gross marginLowest in 5 years85.0%
    85.0%88.1%
    Against its peers: 5 of 7Peers' median 86.6%
  • Operating marginAbove its median39.4%
    -2.1%48.2%
    Against its peers: 2 of 7Peers' median -66.6%
  • Net marginAt its median32.7%
    -4.9%37.2%
    Against its peers: 2 of 7Peers' median -60.1%
  • Return on equityAt its median21.2%
    -3.3%23.9%
    Against its peers: 2 of 7Peers' median -4.7%
  • Free cash flow marginBelow its median26.5%
    -7.2%44.0%
    Against its peers: 3 of 7Peers' median -39.9%
  • Revenue growthLowest in 5 years9.6%
    9.6%22.1%
    Against its peers: 4 of 7Peers' median 5.8%
  • Debt to EBITDAAbove its median0.80×
    0.18×3.60×
    Against its peers: 4 of 4Peers' median 0.04×
  • Current ratioBelow its median2.90
    2.694.83
    Against its peers: 7 of 7Peers' median 3.98

Peers: US companies of the same industry (of its sector when the industry has too few) from a tenth to ten times its market value, the six closest in size. Updated weekly.

Vertex Pharmaceuticals ownership

Institutions
95.84%
Institutional holders
1,831 (+62)
Free float
99.77%

Who owns the shares

Institutions 95.8% Others 4.2%
As of 30 Jun 2026

Shares free to trade

Free float 252.88M shares ·99.8% Closely held 579.41K shares ·0.2%

Closely held shares belong to insiders, founders and owners of more than 5%, and seldom change hands. The free float is the rest: the shares anyone can buy and sell.

Insider trading

QuarterPurchasesSalesShares acquiredShares disposed of
Q4 202600916.970.00
Q3 20260330.32K9.87K
Q2 202601122.07K22.96K
Q1 2026056261.02K323.45K

Shares outstanding

Basic shares Diluted shares Change in diluted shares
Fiscal yearBasic sharesDiluted sharesChange in diluted shares
FY2025255.70M258.00M+0.04%
FY2024257.50M257.90M-1.00%
FY2023257.70M260.50M+0.54%
FY2022256.10M259.10M-0.31%
FY2021257.70M259.90M-1.33%

Common questions about Vertex Pharmaceuticals's financials

Source: Financial Modeling Prep

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