VRTX

Vertex Pharmaceuticals
D

VRTX

Arincen78/100B

If you had invested in Vertex Pharmaceuticals ago, it would be worth $5,898 today, against $4,096 in SPY and $6,368 in QQQ.

ArincenArincen ScoreBeta

78/100

Six parts of the company, five checks each, from its own reported figures. A part scores the checks it passes out of 10; the score is their average out of 100.

Profitability4

Plus shows the checks behind each part of the score, what passed, what failed and the figure it read, for every stock.

Cash8

Plus shows the checks behind each part of the score, what passed, what failed and the figure it read, for every stock.

Valuation6.7

Plus shows the checks behind each part of the score, what passed, what failed and the figure it read, for every stock.

Growth10

Plus shows the checks behind each part of the score, what passed, what failed and the figure it read, for every stock.

Financial strength8

Plus shows the checks behind each part of the score, what passed, what failed and the figure it read, for every stock.

Shareholders10

Plus shows the checks behind each part of the score, what passed, what failed and the figure it read, for every stock.

Figures to FY2025; the price as of today.

Vertex Pharmaceuticals key facts

Style
Growth stock · 5.5/10Growth 5.5 · Value 1.6
Day range
536.41 – 542.98
52-week range
410.50 – 568.67
Market capitalization
136.63B USD
P/E
34.41
PEG ratio
2.01
EPS
15.66
EPS growth forecast (FY2026)
-1.2%
Volume
4,708
Beta
0.32
ESG score
51.3/100Environment 49 · Social 48 · Governance 58
Sector
Healthcare
Industry
Biotechnology
CEO
Reshma Kewalramani
Employees
6K
Website
vrtx.com
IPO date
24 Jul 1991

Vertex Pharmaceuticals earnings

Next earnings · Q4 FY2026
EPS estimate
4.20 USD
Revenue estimate
3.50B USD
Last quarter · Q3 FY2026
EPS4.76Missed -1.2%Revenue3.44BBeat +0.6%

Revenue

ReportedEstimate

EPS

ReportedEstimate
PeriodReport dateEPS estimateReported EPSSurpriseEPS growthRevenue estimateReported revenueSurpriseRevenue growth
Q1 FY20274.64——+3.83%3.47B——+16.19%
Q4 FY20264.20——-16.50%3.50B——+9.59%
Q3 FY20264.824.76-1.24%-0.83%3.42B3.44B+0.62%+11.85%
Q2 FY20264.744.73-0.21%+4.65%3.23B3.33B+3.20%+12.45%
Q1 FY20264.244.47+5.42%+10.10%2.99B2.99B-0.24%+7.82%
Q4 FY20255.115.03-1.57%+26.38%3.18B3.19B+0.18%+9.55%
Q3 FY20254.574.80+5.03%+9.59%3.06B3.08B+0.55%+10.99%
Q2 FY20254.294.52+5.36%—2.91B2.96B+2.01%+12.53%

Analysts' estimates for FY2026 over the last 7 days:EPS Revenue How the estimates moved

Vertex Pharmaceuticals analyst forecast

12-month price target
580.20 USD
+7.67%

Analysts' 1-year price targets range from 350.00 to 665.00, with an average of 580.20.

Past year
1-year forecast
Strong sellStrong buy
Strong buy
24 ratings
Buy
21
Hold
2
Sell
1

12-month price target

Highest target665.00
Average target580.20
Lowest target350.00
Current price538.89

Vertex Pharmaceuticals valuation

Price to earnings ratio (TTM)
34.41
Forward P/E (FY2026)
29.62
Price to sales (TTM)
10.55
Price to book
6.53
EV / EBITDA (TTM)
27.54

Capital structure

Market capitalization
136.63B USD
+
Total debt
6.48B USD
−
Cash and short-term investments
6.30B USD
=
Enterprise value
136.80B USD

Valuation over time

P/EForward P/EForward P/E · EstimateEstimate
Fiscal yearP/EForward P/EP/SP/BEV/EBITDA
FY2028 (est.)22.28————
FY2027 (est.)26.7922.28———
FY2026 (est.)29.6226.79———
Now (TTM)34.4127.1310.556.5327.54
FY202529.3224.939.606.2123.57
FY2024-193.6121.799.416.32207.43
FY202328.9615.0410.625.9620.69
FY202222.2715.048.285.3214.51
FY202124.1615.047.475.6017.40

Vertex Pharmaceuticals against its own history

Each figure in the latest fiscal year against the same figure from FY2021 to FY2025: the range, its median (the line) and the latest (the dot, green on the good side of the median). The P/E is today's against its daily readings of five years.

Its peers: Moderna, Regeneron Pharmaceuticals, Revolution Medicines, United Therapeutics, Incyte, and Insmed, the US Biotechnology companies closest to it in size, each in its own latest fiscal year: their median (the line) and its rank among them, first being the best.

  • Gross marginLowest in 5 years85.6%
    85.6%88.1%
    Against its peers: 4 of 7Peers' median 86.6%
  • Operating marginBelow its median34.8%
    -2.1%48.2%
    Against its peers: 2 of 7Peers' median -66.6%
  • Net marginAt its median32.9%
    -4.9%37.2%
    Against its peers: 2 of 7Peers' median -60.1%
  • Return on equityAt its median21.2%
    -3.3%23.9%
    Against its peers: 2 of 7Peers' median -4.7%
  • Free cash flow marginBelow its median26.6%
    -7.2%44.0%
    Against its peers: 3 of 7Peers' median -39.9%
  • Revenue growthLowest in 5 years8.9%
    8.9%22.1%
    Against its peers: 4 of 7Peers' median 5.8%
  • Debt to EBITDAAbove its median0.42×
    0.18×3.60×
    Against its peers: 3 of 4Peers' median 0.04×
  • Current ratioBelow its median2.90
    2.694.83
    Against its peers: 7 of 7Peers' median 3.98

Peers: US companies of the same industry (of its sector when the industry has too few) from a tenth to ten times its market value, the six closest in size. Updated weekly.

Vertex Pharmaceuticals growth and profitability

Revenue (TTM)
12.95B USD
Net income (TTM)
3.98B USD
Gross margin
85.82%
Operating margin
33.23%
Net margin
30.70%

Revenue / Net income

Revenue Net income Net margin
PeriodRevenueGrowthNet incomeGrowthGross marginOperating marginNet marginEBITDAGrowth
FY202512.00B+8.90%3.95B—85.55%34.77%32.94%4.87B+900.68%
FY202411.02B+11.66%-535.60M-114.80%86.11%-2.11%-4.86%486.30M-89.44%
FY20239.87B+10.51%3.62B+8.96%87.21%38.83%36.68%4.61B+3.83%
FY20228.93B+17.91%3.32B+41.84%87.90%48.23%37.20%4.44B+52.03%
FY20217.57B+22.06%2.34B-13.63%88.06%36.73%30.92%2.92B-11.17%

Vertex Pharmaceuticals revenue breakdown

By product

FY2025
TRIKAFTA/KAFTRIO: 86.2%ALYFTREK: 7.0%Manufactured Product, Other: 6.9%86.2%TRIKAFTA/KAFTRIO7.0%ALYFTREK6.9%Manufactured Product, Other
SegmentRevenueShare of revenueChange on the year
TRIKAFTA/KAFTRIO10.31B86.2%+0.7%
ALYFTREK837.80M7.0%—
Manufactured Product, Other820.10M6.9%+4.9%

By region

FY2025
United States: 45.9%Non-US: 33.1%Europe: 21.0%45.9%United States33.1%Non-US21.0%Europe
RegionRevenueShare of revenueChange on the year
United States7.55B45.9%+12.9%
Non-US5.45B33.1%—
Europe3.46B21.0%+0.2%

How Vertex Pharmaceuticals makes its money

TRIKAFTA/KAFTRIO10.31B 85.9%
ALYFTREK837.80M 7.0%
Manufactured Product, Other820.10M 6.8%
Revenue12.00B 100.0%
Cost of revenue1.81B 15.1%
Gross profit10.27B 85.6%
Research and development3.75B 31.3%
Selling and administration1.75B 14.6%
Other operating expenses587.40M 4.9%
Operating income4.17B 34.8%
Tax690.00M 5.7%
Net income3.95B 32.9%

FY2025, in USD. Each band is as wide as its money; the percentage is its share of revenue.

Vertex Pharmaceuticals financial health

Cash and short-term investments
6.30B USD
Total debt
6.48B USD
Net cash
-175.10M USD
Free cash flow (TTM)
3.20B USD
Current ratio
2.34
Debt to equity
0.31
Piotroski score
4 / 9
Altman Z-score
8.86

Cash, debt and free cash flow

Cash and short-term investments Total debt Free cash flow
Fiscal yearCash and short-term investmentsTotal debtFree cash flow
FY20256.61B2.04B3.19B
FY20246.12B1.75B-790.30M
FY202311.22B808.40M3.28B
FY202210.78B899.70M3.93B
FY20217.52B967.40M2.41B

Vertex Pharmaceuticals ownership

Institutions
95.84%
Institutional holders
1,831 (+62)
Free float
99.77%

Who owns the shares

Institutions 95.8% Others 4.2%
As of 30 Jun 2026

Shares free to trade

Free float 252.96M shares ·99.8% Closely held 579.26K shares ·0.2%

Closely held shares belong to insiders, founders and owners of more than 5%, and seldom change hands. The free float is the rest: the shares anyone can buy and sell.

Insider trading

QuarterPurchasesSalesShares acquiredShares disposed of
Q4 202600916.970.00
Q3 20260330.32K9.87K
Q2 202601122.07K22.96K
Q1 2026056261.02K323.45K

Shares outstanding

Basic shares Diluted shares Change in diluted shares
Fiscal yearBasic sharesDiluted sharesChange in diluted shares
FY2025255.70M258.00M+0.04%
FY2024257.50M257.90M-1.00%
FY2023257.70M260.50M+0.54%
FY2022256.10M259.10M-0.31%
FY2021257.70M259.90M-1.33%

Source: Financial Modeling Prep

Related Instruments

Title: Vertex Pharmaceuticals

Sector: Healthcare
Industry: Biotechnology
Vertex Pharmaceuticals is an American biopharmaceutical company in the business of researching, developing, manufacturing and marketing small molecule drugs for human patients with serious diseases. The company was founded by Joshua S. Boger in 1989 and is headquartered in Boston, Massachusetts. Some of the diseases impacted by its therapies include cystic fibrosis; infectious diseases, including viral infections, such as influenza and bacterial infections; rheumatoid arthritis, cancer, inflammatory bowel disease and neurological disorders. The company was one of the early pioneers of rational drug design rather than combinatorial chemistry.

Common questions about Vertex Pharmaceuticals stock